yes Samson was on Novolog for years. And he did pretty good with it, but it was so nice with Fiasp to just be able to bolus for what he ate afterwards, rather than guessing before meals.
I’ve heard so many stories of Fiasp being much better at first, but then becoming worse after using it for a while. A lot of people have reported that.
I appreciate the consistency I have had with NovoLog.
In the pod, Day 1 = Day 2 = Day 3
And in the time I’ve used it, Year 1 = Year 2 = Year 3
I’m at year 5 with it now, and I’m still happy with it.
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For everyone that tried Fiasp and has issues.
Try Lyumjev. It is basically the ultra rapid version of Humalog (like Fiasp is for Novolog.)
I had issues with Fiasp and what I assume the Tandem cartridge used.
Same tandem pump for me, with Lyumjev, I have used them 4 to 5 days and ran until the pump said ZERO without issues.
Lyumjev is a newer insulin. Not sure if you get it covered under your insurance.
I pay out of pocket, but I use their insulin discount/waiver thing, and I pay $35 per month (3 vials per month for me.) So cost is not a real factor.
Warning, where Fiasp would sometimes sting, Lyumjev can actually hurt a little, when injecting.
I have had bruising around the infusion set, which is also unheard of for me.
These are not all the time, and were mainly just at the start of using it. But I wanted to make note of this.
That being said, I use the exact same profile for Lyumjev as I did for Fiasp. It works a little different, but I really like it.
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I had a visit with a diabetes educator today, and she mentioned ultra-rapid insulin being tested for insulin pumps. I found this 09/29/2025 press release from Tandem announcing that Lyumjev has been officially approved for the t:slim X2: https://investor.tandemdiabetes.com/news-releases/news-release-details/tandem-tslim-x2-insulin-pump-now-compatible-lyumjev-ultra-0
Has anyone else tried Lyumjev with a pump? Have you noticed a marked difference compared to Humalog or Novolog? Or any pump issues, such as more failed infusion sites (or pain/bruising like Hammer mentioned)?
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I’ve used both Fiasp and Lyumjev in Omnipod for several years. I’ve also tried Humalog and Novolog in pods. I found that absorption issues occur with all 4 of these insulins, so I lately have limited the pump to basal and a small partial bolus for meals. If i try to bolus more than about 3-4 units with the pods, the bolus seems to have either a reduced effect or a time delayed effect. So I normally will use Afrezza for 1/2 or more of the bolus for most meals and most corrections and I limit the pump to 2 or 3 units max bolus. Alternately I occasionally use a syringe bolus in the abdomen or thigh.
To answer your question, yes I have had infusion site problems with both Fiasp and Lyumjev. I have found though, despite the limitations I put on the pump bolus, the Fiasp and Lyumjev need a shorter pre-meal delay compared to Novolog or Humalog. The faster insulins seem to go to work quicker as long as I don’t overload the site. The two fast insulins seem to work identically for me.
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