Remission of T2 upon weight loss

This link is only to the abstract page .

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)33102-1/fulltext?elsca1=tlpr

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It’s nice to see a good study confirm what has been suspected to be true in cases of v high BMI patients with T2 diabetes.

But we should remain aware that only a percentage of patients with T2 can be cured with weight loss. T2’s as a group are nowhere near as homogeneous as T1’s, and we know how different T1’s are.

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Really interesting. I saw this recent study as well, suggesting that obesity-induced insulin resistance (in mice) can be caused by an antibody and reversed by the removal of said antibody. So much about T2 we don’t really understand, IMO.

https://www.jci.org/articles/view/89333

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I see so much with mice that I am starting to think they need to use a different animal. It seems like they cure diabetic mice every week!
:grinning:

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Possoms ?

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Mice are used mostly because they are an adequate first research step. They have short lives and because they reproduce quickly, allow for generational studies very easily. Also, there is the ability to easily raise mice with specific problems, i.e. diabetes…

While these things are great for researchers to test their theories, they of course don’t translate well into human solutions. When one reads a mice study, one should look for the neat idea being tested, and banish the thought that it will apply to themselves.

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