Not a wearable like a watch, still too large. MIT researchers have been successful in using Raman Spectroscopy to fairly accurately measure blood glucose levels. They are now trying to miniaturize it to a wearable.
We will see. I always thought that Raman was the way. The problem to me is how to power the device.
Oooh, I love figure 4:
The link is to the (high res)[https://pubs.acs.org/cms/10.1021/acs.analchem.5c01146/asset/images/large/ac5c01146_0004.jpeg] picture. FUD downsamples so the picture above may not be very helpful. I cropped the relevant part out here, for everyone’s entertainment:
It’s entertaining because as I observed to @carlosluis (IRC) on another thread the Dexcom reads high WRT Abbott and, in this case, even produces two spurious lows! Note that in this non-D dude the “reference” BG, which is likely to be accurate, never goes as low as 90mg/dL after the start (he was probably strapped to a bed so this is not surprising).
The cross-over points occur first at a little under 90mg/dL but then are apparently all over the place however the interstitial delay of both sensors is affected by any smoothing within the reported results (smoothing causes a delay in the reported results).
I think the uncalibrated Raman results are unsmoothed as well but there seems to be no smoothing on the calibrated results either. So it looks like both sensors smooth significantly but the difference with the reference BG suggests that the assumed interstitial delay might be falacious. That latter observation is extraordinarily interesting; Raman is first, BG is nominally second and Dexcom and Abbott distant and well smoothed losers, initially, then weird things happen.
Notice that this isn’t random; the BG is consistently synced, with a delay, to the calibrated Ramen but the sensors show peaks which match both yet are variously delayed and confused.
This was a non-D but if the iCGMs can’t keep up with a non-D I hate to imagine how they deal with us.
