How to apply Flonase (Fluticasone) for adhesive allergy


Hi, friends.

Lately, I’ve been having some pretty significant discomfort with the Omnipod adhesive. I’d estimate this has been happening for at least the last 12 months, but it seems to have become worse lately. The rash after removal is lasting longer, and the itching has intensified. As a point of comparison, the Dex adhesive doesn’t seem to bother me at all.

My question is when trialing flonase generic spray on the site before applying the Pod, is there such a thing as too much spray?


I used Flonase under my pods for quite a while last year. I asked multiple CDEs if there was a downside risk to my skin by spraying Flonase on it routinely (I thought I’d read about skin thinning or discoloration somewhere I never found again), and they said they were unaware of any issues.

I ended up wiping down the outside of a sandwich bag with an alcohol wipe to sanitize it, let it dry, spray a couple sprays of Flonase on the bag, and then wipe it generously on the area where I would put the pod. This gave me even distribution and full coverage which was hard to get when spraying directly from the Flonase, especially laterally, onto my skin.

I hope that helps…unless I misunderstood the question.


Oh, thank you! This is precisely the kind of info I was hoping for. I was standing in the pharmacy trying to picture HOW to get the sprayer to work laterally.

Great tip!


@Irish, we have never run into trouble when using Flonase yet (we don’t do it regularly). We do make sure that the skin is absolutely dry before going to the next step (which is typically a barrier adhesive for us—we use SkinTac).