I just posted a blog which is a general update to research on Golimumab (sold as Simponi). There are three clinical trials underway right now:
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Very interesting write-up, @joshualevy, thank you!
I would be very surprised if it was effective in any way for long-standing T1Ds, but who knows. The other two trials should be interesting!
I wonder what the long-term consequences of TNF-alpha inhibition could be. TNF-alpha is a pretty important factor in the immune system.
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That exact issue came up the first time I blogged on Golimumab. Comment #3 in the list here:
https://www.blogger.com/comment.g?blogID=5472921328078253036&postID=4726751583902218725
describes the safety data we have so far.
Joshua
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Thanks!