My Tresiba dose varies a bit during the month, but it’s generally not higher than .32 U/kg.
Tresiba generally works well for me. Every basal insulin has its pros and cons. My basal needs are higher in the evening, and that’s been a challenge on Tresiba. I tried taking Tresiba 2x a day. At first I thought it was helping, but eventually I realized that it really wasn’t solving the problem for me.
Tresiba seems to take much longer to kick in for me than others. I can be as late as 12 hours on my dose before I begin to notice bg values trending slightly upward. If I’m really late or miss a dose, I won’t really feel it until almost 24 hours later. Over time I’ve realized that while Tresiba is marketed to be flexible on timing, it’s much better to take it at nearly the exact time every day (within 1-2 hours at least). Otherwise, I will have upward trends 12-24 hours after the time it should have been taken. I’m not sure if I’m the only one that experiences this; it seems like other people report a lot more flexibility on their timing. Sometimes I wonder if they’re just not attributing upward trends at the 24 hour to a late Tresiba dose.
I generally don’t notice a dose change of 1 unit until 1.5-2 days after I’ve changed it. My doctor has suggested that I switch back to Lantus or try Levemir so that I can handle exercise and monthly hormone variations more easily. I’m trying out a couple of other things first, but if those don’t work, then I will switch at my next appointment.