My guess is that sinus and headache issues are listed under Tresiba side effects because they’re a hugely common issue, and so some fraction of people taking the drug wind up having this problem completely unrelated to drug usage, and then mention this issue to doctors who are then required to list it as a common side effect. Whether it’s much more common in the Tresiba versus placebo group, however, isn’t clear: the idea that 10 percent of people in the trial reported a cold, or a headache, however, doesn’t seem hugely surprising.
Then again, drugs are mysterious and have lots of surprising effects, so I wouldn’t be totally surprised if Tresiba legitimately did cause those symptoms.
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