well i’m guessing they’re looking at the risk rates. Retinopathy is incredibly prevalent for T1Ds; I would assume that most get it eventually, and that even “tight” control doesn’t prevent it if you define tight as 7% or below. You really need to get to the nondiabetic range before it’s an issue if you’re looking at 30-year prevalence rates.
I agree with you, all this article is saying to me, is that if you are in tight control, your clinically actionable retinopathy progression will be slow enough that you can feel ok in spacing out your dilated eye exams.
Interesting bit in Dr. Najeeb’s insulin lecture number 4 about the microvascular risks such as retinopathy being elevated as a function of low c-peptide alone in t1d, even assuming perfect bg management
Well, that is interesting. Really, they got off pretty inexpensively and quickly. They only had to raise $48 million dollars and got an answer showing their treatment, while a promising idea, was not helpful in patients.