How Glycemic Variability impacts HbA1c

Glycation: High GV has no significant effect on T2Ds. For T1Ds, its effect on Glycated Hemoglobin (HbA1c) is extremely minor the lower your mean glucose is. If your average glucose is 140mg/dL, then the difference between low and high variability on A1c is only 0.27%.

High GV has significant effects on glycation only at mean glucose levels far higher than most would find reasonable or properly managed:

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