I found @CarlosLuis 's early 2025 response particularly interesting:
See the remainder of the thread for the link to Tandem’s observation. Maybe it’s canula (plastic) dependent but clearly by that argument it would also be preservative dependent. Site reactions maybe the same, but what about the adhesive interaction?
I don’t see Tandem blaming either the plastic (their canula) or the preservative in that link; neither word occurs in the PDF (the closest leading substrings are “representative” and “replacement”). Cannula gets 39 matches but mostly the ones of interest are about the cannula breaking or becoming completely detached, “dislodged”; the others are instructions.