# Skin graft therapy and insulin production

**URL:** <https://forum.fudiabetes.org/t/skin-graft-therapy-and-insulin-production/1531>\
**Category:** T2 Research\
**Created:** [August 6, 2017, 1:36am UTC](https://forum.fudiabetes.org/t/skin-graft-therapy-and-insulin-production/1531 "2017-08-06T01:36:43Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![Michel](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/michel/32/387_2.png) [@Michel](https://forum.fudiabetes.org/u/Michel)\
**Post date:** [August 6, 2017, 1:36am UTC](https://forum.fudiabetes.org/t/skin-graft-therapy-and-insulin-production/1531/1 "2017-08-06T01:36:43Z")

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[This interesting research](https://www.sciencedaily.com/releases/2017/08/170803122728.htm) in mice at U Chicago Medical center uses CRISPR to express, in skin grafts, a glucagon-like peptide, GLP1, which stimulates insulin production:

> **[Gene therapy via skin could treat many diseases, even obesity: Using CRISPR...](https://www.sciencedaily.com/releases/2017/08/170803122728.htm)**
>
> Scientist have now overcome challenges that have limited the use of gene therapy. They demonstrate how their novel approach with skin transplantation could enable a wide range of gene-based therapies to treat human diseases. The researchers provide...

Far from human application but interesting: if it ever works on humans you could treat Type 2 diabetes with skin grafts, at least for a time.

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**Author:** ![Gary](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/gary/32/1471_2.png) [@Gary](https://forum.fudiabetes.org/u/Gary)\
**Post date:** [August 24, 2017, 2:18am UTC](https://forum.fudiabetes.org/t/skin-graft-therapy-and-insulin-production/1531/2 "2017-08-24T02:18:02Z")

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Lucky mice, LOL, But kidding aside, I have taken GLP1 drugs and found them very useful for a while before they stopped working. I hope that if this ever comes to fruition that they figure a way to extend its usefulness to be permanent.
