# Parent of T1D: need advice tuning treatment of child on MDI

**URL:** https://forum.fudiabetes.org/t/parent-of-t1d-need-advice-tuning-treatment-of-child-on-mdi/6538
**Category:** Child
**Created:** [February 11, 2019, 12:57am UTC](https://forum.fudiabetes.org/t/parent-of-t1d-need-advice-tuning-treatment-of-child-on-mdi/6538 "2019-02-11T00:57:19Z")
**Posts on this page:** 1
**Showing post:** 26

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### Author: ![Eric](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/eric/32/9209_2.png) [@Eric](https://forum.fudiabetes.org/u/Eric)
#### Post date: [February 11, 2019, 7:14pm UTC](https://forum.fudiabetes.org/t/parent-of-t1d-need-advice-tuning-treatment-of-child-on-mdi/6538/26 "2019-02-11T19:14:13Z")

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> [@CodyA](#):
>
> Used to be once a day. Past few days we have moved to 7 units in evening (approx 7:45) and 3 units approx 12 hours later.

One of the great things about Levemir is the shorter duration allows you to customize the basal amounts much better for different times of the day.

Here are the estimates of Levemir durations based on units per kilogram of body weight:

| Dosage amount (units / kilogram) | Average duration |
| --- | --- |
| 0.1 units/kg | 5.7 hours |
| 0.2 units/kg | 12.1 hours |
| 0.4 units/kg | 19.9 hours |
| 0.8 units/kg | 22.7 hours |
| 1.6 units/kg | 23.2 hours |

Make sure you convert body weight to **kilograms**.

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Here is a link, but it is not worded very clearly:

> **[A double-blind, randomized, dose-response study investigating the...](https://pubmed.ncbi.nlm.nih.gov/15855574/)**
>
> This study shows that insulin detemir provides a flat and protracted pharmacodynamic profile.

> **RESULTS:**  
> Duration of action for insulin detemir was dose dependent and varied from 5.7, to 12.1, to 19.9, to 22.7, to 23.2 h for 0.1, 0.2, 0.4, 0.8, and 1.6 units/kg, respectively.

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