# Novel Line of Research for a Cure UPDATE

**URL:** <https://forum.fudiabetes.org/t/novel-line-of-research-for-a-cure-update/605>\
**Category:** D-News\
**Tags:** research, type-1, cure, type-2\
**Created:** [April 25, 2017, 2:05am UTC](https://forum.fudiabetes.org/t/novel-line-of-research-for-a-cure-update/605 "2017-04-25T02:05:18Z")\
**Posts on this page:** 5\
**Page:** 1

<div class="post-metadata">

**Author:** ![docslotnick](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/docslotnick/32/75_2.png) [@docslotnick](https://forum.fudiabetes.org/u/docslotnick)\
**Post date:** [April 25, 2017, 2:05am UTC](https://forum.fudiabetes.org/t/novel-line-of-research-for-a-cure-update/605/1 "2017-04-25T02:05:18Z")

</div>

“Beta cell formation in vivo through cellular networking, integration and processing (CNIP) in wild type adult mice”

Drs. Ralph Defronzo and Bruno Doiron have published research on a novel approach to cure T1 diabetes by using a virus to inject genetic instructions to pancreatic cells in diabetic rats to begin producing insulin. These cells are not originally tasked with insulin production, but the genetic material injected via virus causes them to take on the additional task of insulin production. They have had success in these rats, and are gearing up for further animal trials. Human trials are not expected to begin for at least three years.

Abstract with a download link for the complete article on the bottom left of the page is available here:

> **[Beta Cell Formation in vivo Through Cellular Networking, Integration and...](http://www.eurekaselect.com/138066)**
>
> Insulin replacement therapy is essential in type 1 diabetic individuals and is required in ~40-
> 50% of type 2 diabetics during their lifetime. Prior attemp...

**_UPDATE_**!  
Bruno Doiron has organized a new company, Syner-III, to develop this new revolutionary pathway to a cure. He is seeking $10 million in funding for preclinical trials.  
The only mention I could find was in this poorly written article.

> **[Xconomy: With Gene Therapy for Diabetes, San Antonio Researcher Eyes Funding](https://xconomy.com/texas/2017/05/31/with-gene-therapy-for-diabetes-san-antonio-researcher-eyes-funding/)**
>
> San Antonio --- Most diabetes treatments work by giving the body the insulin it needs to break down sugar. But that approach deals with the symptoms of

With all I’ve read about research for a cure, this is the horse I would be betting on.

---

<div class="post-metadata">

**Author:** ![Michel](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/michel/32/387_2.png) [@Michel](https://forum.fudiabetes.org/u/Michel)\
**Post date:** [April 25, 2017, 3:14am UTC](https://forum.fudiabetes.org/t/novel-line-of-research-for-a-cure-update/605/2 "2017-04-25T03:14:14Z")

</div>

The dream. It would be amazing.

---

<div class="post-metadata">

**Author:** ![docslotnick](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/docslotnick/32/75_2.png) [@docslotnick](https://forum.fudiabetes.org/u/docslotnick)\
**Post date:** [June 1, 2017, 1:02am UTC](https://forum.fudiabetes.org/t/novel-line-of-research-for-a-cure-update/605/3 "2017-06-01T01:02:27Z")

</div>

This story has been updated!

---

<div class="post-metadata">

**Author:** ![Michel](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/michel/32/387_2.png) [@Michel](https://forum.fudiabetes.org/u/Michel)\
**Post date:** [June 1, 2017, 8:36am UTC](https://forum.fudiabetes.org/t/novel-line-of-research-for-a-cure-update/605/4 "2017-06-01T08:36:07Z")

</div>

Really interesting! I would love to read more about his new venture.

---

<div class="post-metadata">

**Author:** ![NGallagher](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/ngallagher/32/3147_2.png) [@NGallagher](https://forum.fudiabetes.org/u/NGallagher)\
**Post date:** [January 31, 2018, 2:52am UTC](https://forum.fudiabetes.org/t/novel-line-of-research-for-a-cure-update/605/5 "2018-01-31T02:52:57Z")

</div>

Very “crafty” technique. What a brilliant way to get around the immune system using cells already in place. Convince them to do 1 more task, produce insulin.
