# Microdosing Gvoke rocks! **URL:** \ **Category:** Share\ **Tags:** hypoglycemia, glucagon\ **Created:** [December 26, 2021, 3:20pm UTC](https://forum.fudiabetes.org/t/microdosing-gvoke-rocks/12208 "2021-12-26T15:20:03Z")\ **Posts on this page:** 11\ **Page:** 1
**Author:** ![CatLady](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/catlady/32/36_2.png) [@CatLady](https://forum.fudiabetes.org/u/CatLady)\ **Post date:** [December 26, 2021, 3:20pm UTC](https://forum.fudiabetes.org/t/microdosing-gvoke-rocks/12208/1 "2021-12-26T15:20:03Z")
I went rapidly low about 2 a.m., waking up at 76 on my CGM with that “thumpy” heartbeat feeling. I shoved in glucose tabs until I just couldn’t because I rapidly became nauseous. My blood sugar continued to drop (CGM 52 but fingerstick 37) and I was spacey and drenched in sweat. So my husband grabbed the Gvoke pre-filled syringe and eyeballed a microdose (about 1/4th of the total) and in 10 minutes I started to feel much better and in 20 minutes my blood sugar was 69! In an hour my blood sugar topped out in the 190s (all those glucose tabs) but I was so exhausted I just went to sleep. Used Afrezza this morning to correct and am feeling much better but really am wondering what the heck happened! 😳 😳 ---
**Author:** ![Eric](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/eric/32/9209_2.png) [@Eric](https://forum.fudiabetes.org/u/Eric)\ **Post date:** [December 26, 2021, 4:36pm UTC](https://forum.fudiabetes.org/t/microdosing-gvoke-rocks/12208/2 "2021-12-26T16:36:42Z")
Awesome stuff you are doing! 👍 ---
**Author:** ![MM2](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/mm2/32/3032_2.png) [@MM2](https://forum.fudiabetes.org/u/MM2)\ **Post date:** [December 26, 2021, 9:04pm UTC](https://forum.fudiabetes.org/t/microdosing-gvoke-rocks/12208/3 "2021-12-26T21:04:42Z")
> [@CatLady](#): > > but really am wondering what the heck happened! Any chance you had alcohol ?. ---
**Author:** ![T1Allison](https://avatars.discourse-cdn.com/v4/letter/t/c77e96/32.png) [@T1Allison](https://forum.fudiabetes.org/u/T1Allison)\ **Post date:** [December 27, 2021, 12:09am UTC](https://forum.fudiabetes.org/t/microdosing-gvoke-rocks/12208/4 "2021-12-27T00:09:49Z")
> [@CatLady](#): > > My blood sugar continued to drop (CGM 52 but fingerstick 37) and I was spacey and drenched in sweat. So my husband grabbed the Gvoke pre-filled syringe and eyeballed a microdose (about 1/4th of the total) and in 10 minutes I started to feel much better and in 20 minutes my blood sugar was 69! Holy cow! That sounds super unsettling (understatement)! I’m glad you tested and I’m glad your husband came to your aid! I hope you can move through this without taking on baggage of fear…but I’d totally understand if it sticks with you for a while. I hope you’re proud of yourself for taking care of business, bc that’s what I see! A sucky thing happened, but you were ahead of it!! ❤💪❤💪❤ ---
**Author:** ![CatLady](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/catlady/32/36_2.png) [@CatLady](https://forum.fudiabetes.org/u/CatLady)\ **Post date:** [December 27, 2021, 12:20am UTC](https://forum.fudiabetes.org/t/microdosing-gvoke-rocks/12208/5 "2021-12-27T00:20:16Z")
Just two 4 ounce glasses of sparkling wine, one before dinner and one after. And overall my activity level was not as much as on other holidays. Also decreased my dinner bolus a bit due to the wine on board. I duuno… ---
**Author:** ![CatLady](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/catlady/32/36_2.png) [@CatLady](https://forum.fudiabetes.org/u/CatLady)\ **Post date:** [December 27, 2021, 12:33am UTC](https://forum.fudiabetes.org/t/microdosing-gvoke-rocks/12208/6 "2021-12-27T00:33:34Z")
> [@T1Allison](#): > > hope you can move through this without taking on baggage of fear Thank you, I am having a hard time writing a reply but want you to know how much I appreciate your support and encouragement. Nameste! ❤ 🙏 🌈 ---
**Author:** ![CatLady](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/catlady/32/36_2.png) [@CatLady](https://forum.fudiabetes.org/u/CatLady)\ **Post date:** [December 27, 2021, 6:25pm UTC](https://forum.fudiabetes.org/t/microdosing-gvoke-rocks/12208/7 "2021-12-27T18:25:02Z")
Follow-up question for those who have used glucagon: Did you experience atypical insulin resistance for any length of time following its use? I was really insulin resistant all day Sunday, both before and after a scheduled pod change. Today, however, I have needed extra carbs after breakfast. Thoughts? ---
**Author:** ![MarkP](https://avatars.discourse-cdn.com/v4/letter/m/b3f665/32.png) [@MarkP](https://forum.fudiabetes.org/u/MarkP)\ **Post date:** [January 2, 2022, 12:58am UTC](https://forum.fudiabetes.org/t/microdosing-gvoke-rocks/12208/8 "2022-01-02T00:58:12Z")
Is there going to be a more stable glucagon? Or something that could be placed into a pump so that low BGs could be handled via looping? ---
**Author:** ![TiaG](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/tiag/32/594_2.png) [@TiaG](https://forum.fudiabetes.org/u/TiaG)\ **Post date:** [January 2, 2022, 1:15am UTC](https://forum.fudiabetes.org/t/microdosing-gvoke-rocks/12208/9 "2022-01-02T01:15:02Z")
I think GVoke is shelf-stable for a year. They haven’t yet approved it for pumps but I think that’s a followup step. ---
**Author:** ![TiaG](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/tiag/32/594_2.png) [@TiaG](https://forum.fudiabetes.org/u/TiaG)\ **Post date:** [January 2, 2022, 1:15am UTC](https://forum.fudiabetes.org/t/microdosing-gvoke-rocks/12208/10 "2022-01-02T01:15:49Z")
But there’s also one called [Zegalogue](https://www.zegalogue.com/hcp/?gclid=Cj0KCQiAlMCOBhCZARIsANLid6Y0bU9Ma7SlyAy9Ko2XUCWJxi82CSx361g0nEHqcRU0JjbgDCCFKIEaAh_yEALw_wcB&gclsrc=aw.ds) (dasiglucagon) made by Zealand pharmaceuticals that will eventually be approved for just this purpose. I think first is the “emergency glucagon” and only after that will they approve it for looping ---
**Author:** ![MarkP](https://avatars.discourse-cdn.com/v4/letter/m/b3f665/32.png) [@MarkP](https://forum.fudiabetes.org/u/MarkP)\ **Post date:** [January 2, 2022, 3:14am UTC](https://forum.fudiabetes.org/t/microdosing-gvoke-rocks/12208/11 "2022-01-02T03:14:22Z")
Fantastic, I feel like this is the missing link, I’d love to have a gentle version though because I feel like the ability to go from 50 to 100 is much better than 50 to 200.