# Effect of preservatives on insulin effectivity and site issues

**URL:** <https://forum.fudiabetes.org/t/effect-of-preservatives-on-insulin-effectivity-and-site-issues/16019>\
**Category:** Tips, Tech & Gear\
**Tags:** insulin\
**Created:** [May 1, 2026, 11:12pm UTC](https://forum.fudiabetes.org/t/effect-of-preservatives-on-insulin-effectivity-and-site-issues/16019 "2026-05-01T23:12:23Z")\
**Posts on this page:** 1\
**Showing post:** 8

<div class="post-metadata">

**Author:** ![jbowler](https://avatars.discourse-cdn.com/v4/letter/j/e274bd/32.png) [@jbowler](https://forum.fudiabetes.org/u/jbowler)\
**Post date:** [May 3, 2026, 12:31am UTC](https://forum.fudiabetes.org/t/effect-of-preservatives-on-insulin-effectivity-and-site-issues/16019/8 "2026-05-03T00:31:08Z")

</div>

The @Sjwprod discussion is continued in the original thread, here:

> [@Effectiveness of NovoLog vs Humalog in a pump](https://forum.fudiabetes.org/t/effectiveness-of-novolog-vs-humalog-in-a-pump/10978/26):
>
> All of the studies are old and outdated with regard to insulin use in pumps. Look for studies that specifically note that the insulins being used are formulated to be approved for use in pumps.

That thread is important input but there are a lot of issues and this is a core issue for pump users. Hum; I should have been more clear, MDI has site issues and loss of efficacy issues too. I was primarily targeting issues for pump users with regard to the specific formulation of the insulin, the additives (the “salts”, the preservatives) as opposed to the biochemical formula of the insulin itself. That said, all input is welcome; this is FUD.

---

_[View the full topic](https://forum.fudiabetes.org/t/effect-of-preservatives-on-insulin-effectivity-and-site-issues/16019)._