Discussion on Metformin use by T1's

[docslotnick]

@cardamom

of drugs, but I always worry about potentially increasing yeast infections

Yes, that can be a problem. It also can be dangerous if you have kidney problems.

In T1’s the bigger problem is DKA. But I take a large enough TDD of insulin to make that problem moot.

[Jen]

@cardamom

I am intrigued by the SGLT-2 inhibitor class of drugs, but I always worry about potentially increasing yeast infections with them—I’ve heard from a few women who have taken them that they discontinued due to that and increased UTIs, from the increased glucose spill over in the urine.

I tried an SGLT-2 inhibitor and it was amazing for blood glucose control and probably would have helped with weight loss. But i quit after sis weeks due to the reasons above.

[cardamom]

@docslotnick

In T1’s the bigger problem is DKA. But I take a large enough TDD of insulin to make that problem moot.

That makes sense—seems like in full on T1s (i.e. not early LADA/honeymooning), ideally SGLT-2 inhibitors would be paired with a recommended minimum TDD to remain over for that individual.