# Beta cell proliferation in adults

**URL:** https://forum.fudiabetes.org/t/beta-cell-proliferation-in-adults/5816
**Category:** T1 Research
**Created:** [December 14, 2018, 2:47pm UTC](https://forum.fudiabetes.org/t/beta-cell-proliferation-in-adults/5816 "2018-12-14T14:47:06Z")
**Posts on this page:** 5
**Page:** 1

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### Author: ![TiaG](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/tiag/32/594_2.png) [@TiaG](https://forum.fudiabetes.org/u/TiaG)
#### Post date: [December 14, 2018, 2:47pm UTC](https://forum.fudiabetes.org/t/beta-cell-proliferation-in-adults/5816/1 "2018-12-14T14:47:06Z")

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I thought this was an interesting study. Of course, they took their recipe book from insulinomas, which are basically benign forms of cancer. And you don’t want a bunch of off-target effects, and this isn’t even a mouse study, it’s a cell culture study as far as I can tell. But…the idea is pretty neat:

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### Author: ![Trying](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/trying/32/4078_2.png) [@Trying](https://forum.fudiabetes.org/u/Trying)
#### Post date: [December 14, 2018, 8:15pm UTC](https://forum.fudiabetes.org/t/beta-cell-proliferation-in-adults/5816/2 "2018-12-14T20:15:46Z")

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The last statement though was that it would be translatable to human beings in 5-8 years! That almost sounds like a cure! Or did I misunderstand??!

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### Author: ![TiaG](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/tiag/32/594_2.png) [@TiaG](https://forum.fudiabetes.org/u/TiaG)
#### Post date: [December 14, 2018, 8:19pm UTC](https://forum.fudiabetes.org/t/beta-cell-proliferation-in-adults/5816/3 "2018-12-14T20:19:09Z")

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well they also have to figure out how to stop our immune system from destroying the new beta cells. Plus, by translatable to humans I am assuming they mean “phase 1 safety trials” – not “you can go pick these up in the local clinic in 5 to 8 years.” That could mean 10 to 15 years or more till it would even be available if everything went to plan.

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### Author: ![Trying](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/trying/32/4078_2.png) [@Trying](https://forum.fudiabetes.org/u/Trying)
#### Post date: [December 14, 2018, 8:24pm UTC](https://forum.fudiabetes.org/t/beta-cell-proliferation-in-adults/5816/4 "2018-12-14T20:24:16Z")

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Good points! I was wishful thinking! I wonder though if immunosuppressants would even be needed IF we could just get a new supply every so often once their level is reduced to some minimal threshold.

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### Author: ![DoubleBee](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/doublebee/32/5705_2.png) [@DoubleBee](https://forum.fudiabetes.org/u/DoubleBee)
#### Post date: [January 20, 2019, 2:34pm UTC](https://forum.fudiabetes.org/t/beta-cell-proliferation-in-adults/5816/5 "2019-01-20T14:34:26Z")

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I agree with @TiaG while this is promising to move towards a full cure it will have to come in two phases.

1. Address the autoimmune disease
2. Address recovery of beta cells

I agree with the 10-15 year timeline for this but the silver lining is that beta cell proliferation will also be of benefit to type 2 diabetics which is a 10x size market so the funding will be there as soon as there is compelling evidence that this (or a derived technique) can be taken through clinical trials to market.
