# A Clinical Screening Tool Identifies T1 in Adults

**URL:** <https://forum.fudiabetes.org/t/a-clinical-screening-tool-identifies-t1-in-adults/585>\
**Category:** Type 1 & LADA\
**Tags:** lada, type-1, ddx\
**Created:** [April 23, 2017, 4:09am UTC](https://forum.fudiabetes.org/t/a-clinical-screening-tool-identifies-t1-in-adults/585 "2017-04-23T04:09:24Z")\
**Posts on this page:** 4\
**Page:** 1

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**Author:** ![britt\_j](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/britt_j/32/55_2.png) [@britt\_j](https://forum.fudiabetes.org/u/britt_j)\
**Post date:** [April 23, 2017, 4:09am UTC](https://forum.fudiabetes.org/t/a-clinical-screening-tool-identifies-t1-in-adults/585/1 "2017-04-23T04:09:24Z")

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A clinical screening tool identifies autoimmune diabetes in adults;  
Fourlanos et al; Diabetes Care; 2006 May;29(5):970-5.

> CONCLUSIONS: At least two [of 5] distinguishing clinical features are found in a majority of patients with LADA at diagnosis and can be used to identify adults with diabetes at higher risk for LADA.

> tl;dr: On the basis of these findings, _five_ distinguishing clinical features were significantly more frequent in subjects with LADA than in subjects with type 2 diabetes at diagnosis (Fig. 1). These were

> 1. age of diabetes onset \<50 years
> 2. acute symptoms of polydipsia and/or polyuria and/or unintentional weight loss before diagnosis
> 3. BMI \<25 kg/m2
> 4. a personal history of DR3- and/or DR4-related autoimmune disease
> 5. a family history of DR3- and/or DR4-related autoimmune disease.

> A majority (75%) of subjects with LADA and a minority (24%) of type 2 diabetic subjects had at least two distinguishing clinical features (LADA clinical risk score ≥2).

> **[A clinical screening tool identifies autoimmune diabetes in adults - PubMed](https://pubmed.ncbi.nlm.nih.gov/16644622/)**
>
> At least two distinguishing clinical features are found in a majority of patients with LADA at diagnosis and can be used to identify adults with diabetes at higher risk for LADA.

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**Author:** ![rgcainmd](https://avatars.discourse-cdn.com/v4/letter/r/a5b964/32.png) [@rgcainmd](https://forum.fudiabetes.org/u/rgcainmd)\
**Post date:** [April 23, 2017, 4:55am UTC](https://forum.fudiabetes.org/t/a-clinical-screening-tool-identifies-t1-in-adults/585/2 "2017-04-23T04:55:12Z")

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Hopefully more physicians will screen for these clinical features and fewer adults with LADA will be misdiagnosed with Type 2!

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**Author:** ![britt\_j](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/britt_j/32/55_2.png) [@britt\_j](https://forum.fudiabetes.org/u/britt_j)\
**Post date:** [April 23, 2017, 3:04pm UTC](https://forum.fudiabetes.org/t/a-clinical-screening-tool-identifies-t1-in-adults/585/3 "2017-04-23T15:04:48Z")

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I couldn’t agree more…

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**Author:** ![Michel](https://yyz2.discourse-cdn.com/flex030/user_avatar/forum.fudiabetes.org/michel/32/387_2.png) [@Michel](https://forum.fudiabetes.org/u/Michel)\
**Post date:** [April 23, 2017, 6:40pm UTC](https://forum.fudiabetes.org/t/a-clinical-screening-tool-identifies-t1-in-adults/585/4 "2017-04-23T18:40:36Z")

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I love the fact that you excerpted the salient conclusions at the top! That was great.

maybe we should do that every time 🙂