# T2 Research **URL:** https://forum.fudiabetes.org/c/diabetes-type-2-mody/t2-mody-research/63.md?page=1 [Latest](https://forum.fudiabetes.org/latest.md) · [Categories](https://forum.fudiabetes.org/categories.md) · [Tags](https://forum.fudiabetes.org/tags.md) **Page:** 2 --- ## [Skin graft therapy and insulin production](https://forum.fudiabetes.org/t/skin-graft-therapy-and-insulin-production/1531)
**Author:** [@Michel](https://forum.fudiabetes.org/u/Michel)\ **Replies:** 1\ **Last updated:** [August 24, 2017, 2:18am UTC](https://forum.fudiabetes.org/t/skin-graft-therapy-and-insulin-production/1531 "2017-08-24T02:18:02Z")
This interesting research in mice at U Chicago Medical center uses CRISPR to express, in skin grafts, a glucagon-like peptide, GLP1, which stimulates insulin production: Far from human application but interesting: if … --- ## [Broccoli compound for Type 2?](https://forum.fudiabetes.org/t/broccoli-compound-for-type-2/1261)
**Author:** [@TiaG](https://forum.fudiabetes.org/u/TiaG)\ **Replies:** 4\ **Last updated:** [June 16, 2017, 2:24am UTC](https://forum.fudiabetes.org/t/broccoli-compound-for-type-2/1261 "2017-06-16T02:24:29Z")
I'm a little bit skeptical for a few reasons. 1) Taking 100 times the dose that a normal person eats in a serving of broccoli to get a 10 percent reduction in BG levels doesn't seem huge to me. 2) Can eating this really … --- ## [Functional High Intensity Training (F-HIT) lowers insulin resistance for T2Ds](https://forum.fudiabetes.org/t/functional-high-intensity-training-f-hit-lowers-insulin-resistance-for-t2ds/1150)
**Author:** [@MaryPat](https://forum.fudiabetes.org/u/MaryPat)\ **Replies:** 3\ **Last updated:** [June 7, 2017, 5:00pm UTC](https://forum.fudiabetes.org/t/functional-high-intensity-training-f-hit-lowers-insulin-resistance-for-t2ds/1150 "2017-06-07T17:00:05Z")
I ran into this interesting article in Science Daily. I was interested because it involved very short training sessions. The experiment involved 12 T2Ds doing 3 F-HIT workout per week of 10-20 minutes each for 6 weeks. T… --- ## [Metformin OK for T2s with mild renal impairment: FDA update](https://forum.fudiabetes.org/t/metformin-ok-for-t2s-with-mild-renal-impairment-fda-update/1077)
**Author:** [@Michel](https://forum.fudiabetes.org/u/Michel)\ **Replies:** 0\ **Last updated:** [May 28, 2017, 12:48am UTC](https://forum.fudiabetes.org/t/metformin-ok-for-t2s-with-mild-renal-impairment-fda-update/1077 "2017-05-28T00:48:24Z")
Last month, FDA finalized its recommendation on warning labels that Metformin is now OK for use with T2 patients with mild renal function impairment, and with some T2s with moderate renal function impairment: https://w… --- ## [Metformin and gut bacteria](https://forum.fudiabetes.org/t/metformin-and-gut-bacteria/1076)
**Author:** [@MaryPat](https://forum.fudiabetes.org/u/MaryPat)\ **Replies:** 1\ **Last updated:** [May 28, 2017, 12:38am UTC](https://forum.fudiabetes.org/t/metformin-and-gut-bacteria/1076 "2017-05-28T00:38:42Z")
I read the two articles Michel posted about T1Ds and gut bacteria. That was interesting. So I was intrigued when I ran into this article on Metformin and gut bacteria (again!): Metformin alters the gut microbiome of… --- ## [Non-insulin therapy proves successful for T2Ds](https://forum.fudiabetes.org/t/non-insulin-therapy-proves-successful-for-t2ds/1004)
**Author:** [@Michel](https://forum.fudiabetes.org/u/Michel)\ **Replies:** 0\ **Last updated:** [May 22, 2017, 1:59am UTC](https://forum.fudiabetes.org/t/non-insulin-therapy-proves-successful-for-t2ds/1004 "2017-05-22T01:59:42Z")
This interesting study tests a combination of drugs for poorly controlled type 2 diabetics. The outcome: lower A1c by 1% and 1/3 the rate of hypoglycemia compared to insulin! Check this out: To be clear: this stu… --- ## [Baby aspirin therapy won't lower heart disease risk for T2Ds: research](https://forum.fudiabetes.org/t/baby-aspirin-therapy-wont-lower-heart-disease-risk-for-t2ds-research/988)
**Author:** [@Michel](https://forum.fudiabetes.org/u/Michel)\ **Replies:** 2\ **Last updated:** [May 20, 2017, 11:04pm UTC](https://forum.fudiabetes.org/t/baby-aspirin-therapy-wont-lower-heart-disease-risk-for-t2ds-research/988 "2017-05-20T23:04:22Z")
http://www.health.harvard.edu/diabetes/aspirin-therapy-may-not-lower-heart-attack-risk-for-those-with-type-2-diabetes? Really too bad, although not totally unexpected to me, since baby aspirin therapy seems to be mostl… --- ## [Invokana warning: foot and leg amputations](https://forum.fudiabetes.org/t/invokana-warning-foot-and-leg-amputations/955)
**Author:** [@Michel](https://forum.fudiabetes.org/u/Michel)\ **Replies:** 13\ **Last updated:** [May 18, 2017, 2:01am UTC](https://forum.fudiabetes.org/t/invokana-warning-foot-and-leg-amputations/955 "2017-05-18T02:01:46Z")
Invokana is an SGLT-2 inhibitor. The FDA has just asked Johnson & Johnson to display a big box warning about foot and leg amputations: http://in.reuters.com/article/health-diabetes-johnson-johnson-idINKCN18D07X The FD… --- ## [Inconsistent sleep schedule and insulin resistance](https://forum.fudiabetes.org/t/inconsistent-sleep-schedule-and-insulin-resistance/951)
**Author:** [@Michel](https://forum.fudiabetes.org/u/Michel)\ **Replies:** 1\ **Last updated:** [May 17, 2017, 5:10am UTC](https://forum.fudiabetes.org/t/inconsistent-sleep-schedule-and-insulin-resistance/951 "2017-05-17T05:10:08Z")
This study from 2016 shows a fairly definite correlation (which does not mean causality) between inconsistent sleep schedule and increased insulin resistance: “After adjustment for race, menopausal symptoms, sleep du… --- ## [Genetics and Type 2 Diabetes - Broad Institute (Video)](https://forum.fudiabetes.org/t/genetics-and-type-2-diabetes-broad-institute-video/696)
**Author:** [@britt\_j](https://forum.fudiabetes.org/u/britt_j)\ **Replies:** 1\ **Last updated:** [May 2, 2017, 3:38am UTC](https://forum.fudiabetes.org/t/genetics-and-type-2-diabetes-broad-institute-video/696 "2017-05-02T03:38:08Z")
Midsummer Nights' Science: Genetics and \[Type 2\] Diabetes (2014); Broad Institute w/ David Altshuler, Endocrinologist, Geneticist (Video), Harvard/MIT Description: Designing new drugs would be easier if scientists un… --- ## [The Palette Model of Type 2 Diabetes (PDF)](https://forum.fudiabetes.org/t/the-palette-model-of-type-2-diabetes-pdf/593)
**Author:** [@britt\_j](https://forum.fudiabetes.org/u/britt_j)\ **Replies:** 0\ **Last updated:** [April 24, 2017, 12:42am UTC](https://forum.fudiabetes.org/t/the-palette-model-of-type-2-diabetes-pdf/593 "2017-04-24T00:42:20Z")
Painting a new picture of personalised medicine for diabetes by Mark I. McCarthy; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford; Diabetologia (2017) 60:793–799 DOI 10.1007/s00125-017-4210… --- ## [Proposed New Classification System for Diabetes...β-Cell-Centric](https://forum.fudiabetes.org/t/proposed-new-classification-system-for-diabetes-cell-centric/446)
**Author:** [@britt\_j](https://forum.fudiabetes.org/u/britt_j)\ **Replies:** 1\ **Last updated:** [April 12, 2017, 8:04am UTC](https://forum.fudiabetes.org/t/proposed-new-classification-system-for-diabetes-cell-centric/446 "2017-04-12T08:04:43Z")
The Time Is Right for a New Classification System for Diabetes: Rationale and Implications of the β-Cell-Centric Classification Schema. Schwartz SS et al; Diabetes Care. 2016 Feb;39(2):179-86. doi: 10.2337/dc15-1585. … [Previous page](https://forum.fudiabetes.org/c/diabetes-type-2-mody/t2-mody-research/63.md)