# T1 Research **URL:** https://forum.fudiabetes.org/c/diabetes-type-1-lada/t1-research/62.md?page=3 [Latest](https://forum.fudiabetes.org/latest.md) · [Categories](https://forum.fudiabetes.org/categories.md) · [Tags](https://forum.fudiabetes.org/tags.md) **Page:** 4 --- ## [Symlin/Insulin combo reduces spikes significantly post-meal](https://forum.fudiabetes.org/t/symlin-insulin-combo-reduces-spikes-significantly-post-meal/5072)
**Author:** [@TiaG](https://forum.fudiabetes.org/u/TiaG)\ **Replies:** 8\ **Last updated:** [September 26, 2018, 5:17pm UTC](https://forum.fudiabetes.org/t/symlin-insulin-combo-reduces-spikes-significantly-post-meal/5072 "2018-09-26T17:17:18Z")
Interesting, even though it’s a Phase I so basically just a safety trial. A 97% reduction in post-meal spikes seems pretty impressive; I wonder how it compares to manually doing a separate Symlin injection. However, I’ve… --- ## [NextCell Starts a Phase-I Study of Mesenchymal Stromal Cell Treatment](https://forum.fudiabetes.org/t/nextcell-starts-a-phase-i-study-of-mesenchymal-stromal-cell-treatment/5019)
**Author:** [@joshualevy](https://forum.fudiabetes.org/u/joshualevy)\ **Replies:** 1\ **Last updated:** [September 18, 2018, 8:28am UTC](https://forum.fudiabetes.org/t/nextcell-starts-a-phase-i-study-of-mesenchymal-stromal-cell-treatment/5019 "2018-09-18T08:28:44Z")
I’ve written a blog on a study using a specific type of umbilical cord stem cell to try to cure type-1 diabetes in honeymooners: The good news, is that the study is already running, and should have some very early re… --- ## [This Diabetic Sees Things Differently](https://forum.fudiabetes.org/t/this-diabetic-sees-things-differently/4867)
**Author:** [@ckat](https://forum.fudiabetes.org/u/ckat)\ **Replies:** 67\ **Last updated:** [September 15, 2018, 4:16am UTC](https://forum.fudiabetes.org/t/this-diabetic-sees-things-differently/4867 "2018-09-15T04:16:05Z")
Hey I scour the internet world wide and post great ground breaking stuff on Facebook. Useful Scientific backed stuff you probably won’t hear anywhere else… Like there is a scientist reversing type 1 diabetes with an old… --- ## [Results from a Phase-II Verapamil Trial](https://forum.fudiabetes.org/t/results-from-a-phase-ii-verapamil-trial/4889)
**Author:** [@joshualevy](https://forum.fudiabetes.org/u/joshualevy)\ **Replies:** 0\ **Last updated:** [September 2, 2018, 11:07pm UTC](https://forum.fudiabetes.org/t/results-from-a-phase-ii-verapamil-trial/4889 "2018-09-02T23:07:57Z")
Verapamil has finished a phase-II trial, and I’ve summarized and discussed the results here: --- ## [GABA Starts A Phase-II? Clinical Trial in Honeymooners](https://forum.fudiabetes.org/t/gaba-starts-a-phase-ii-clinical-trial-in-honeymooners/4821)
**Author:** [@joshualevy](https://forum.fudiabetes.org/u/joshualevy)\ **Replies:** 0\ **Last updated:** [August 24, 2018, 5:01am UTC](https://forum.fudiabetes.org/t/gaba-starts-a-phase-ii-clinical-trial-in-honeymooners/4821 "2018-08-24T05:01:07Z")
This blog has two parts. The first part describes a phase-I clinical trial in honeymooners which started recently. The second part summarizes the rest of the GABA (Gamma-Aminobutyric Acid) research done so far in peopl… --- ## [Dr. Faustman Publishes Follow On BCG Data From Phase-I Trial](https://forum.fudiabetes.org/t/dr-faustman-publishes-follow-on-bcg-data-from-phase-i-trial/4540)
**Author:** [@joshualevy](https://forum.fudiabetes.org/u/joshualevy)\ **Replies:** 1\ **Last updated:** [July 21, 2018, 6:54am UTC](https://forum.fudiabetes.org/t/dr-faustman-publishes-follow-on-bcg-data-from-phase-i-trial/4540 "2018-07-21T06:54:16Z")
I just published a long, detailed blog posting on Dr. Faustman’s recent BCG paper. You can read it here: https://cureresearch4type1diabetes.blogspot.com/…/dr-faustm… It is very hard to summarize all the details in one … --- ## [New Blog Post: GNbAC1 Starts A Phase-II? Trial](https://forum.fudiabetes.org/t/new-blog-post-gnbac1-starts-a-phase-ii-trial/4215)
**Author:** [@joshualevy](https://forum.fudiabetes.org/u/joshualevy)\ **Replies:** 9\ **Last updated:** [July 6, 2018, 11:03pm UTC](https://forum.fudiabetes.org/t/new-blog-post-gnbac1-starts-a-phase-ii-trial/4215 "2018-07-06T23:03:32Z")
Posted a new blog on a possible cure for type-1 diabetes which is going through early tests on people. It is called “GNbAC1” and is based on a unique theory of what causes type-1 diabetes. Best of all, they are going to … --- ## [New blog posting on Alpha Difluoromethylornithine (DFMO)](https://forum.fudiabetes.org/t/new-blog-posting-on-alpha-difluoromethylornithine-dfmo/4287)
**Author:** [@joshualevy](https://forum.fudiabetes.org/u/joshualevy)\ **Replies:** 2\ **Last updated:** [June 25, 2018, 2:04pm UTC](https://forum.fudiabetes.org/t/new-blog-posting-on-alpha-difluoromethylornithine-dfmo/4287 "2018-06-25T14:04:04Z")
New blog posting: https://cureresearch4type1diabetes.blogspot.com/2018/06/alpha-difluoromethylornithine-dfmo.html --- ## [New Blog on Results from a Phase-II ATG and GCSF Combination Trial](https://forum.fudiabetes.org/t/new-blog-on-results-from-a-phase-ii-atg-and-gcsf-combination-trial/4061)
**Author:** [@joshualevy](https://forum.fudiabetes.org/u/joshualevy)\ **Replies:** 1\ **Last updated:** [May 22, 2018, 9:05pm UTC](https://forum.fudiabetes.org/t/new-blog-on-results-from-a-phase-ii-atg-and-gcsf-combination-trial/4061 "2018-05-22T21:05:39Z")
I just posted this blog: http://cureresearch4type1diabetes.blogspot.com/2018/05/results-from-phase-ii-atg-and-gcsf.html --- ## [Diverse causes of inflammation in Type 1s](https://forum.fudiabetes.org/t/diverse-causes-of-inflammation-in-type-1s/3662)
**Author:** [@TiaG](https://forum.fudiabetes.org/u/TiaG)\ **Replies:** 2\ **Last updated:** [May 13, 2018, 3:04pm UTC](https://forum.fudiabetes.org/t/diverse-causes-of-inflammation-in-type-1s/3662 "2018-05-13T15:04:11Z")
Another interesting, if preliminary finding: The causes of inflammation in people with Type 1 are diverse – so perhaps using anti-inflammatories that are targeted to the specific ones in a given person could help. (No da… --- ## [Are we closer to a universal screening for T1D?](https://forum.fudiabetes.org/t/are-we-closer-to-a-universal-screening-for-t1d/1986)
**Author:** [@TiaG](https://forum.fudiabetes.org/u/TiaG)\ **Replies:** 28\ **Last updated:** [May 1, 2018, 3:54am UTC](https://forum.fudiabetes.org/t/are-we-closer-to-a-universal-screening-for-t1d/1986 "2018-05-01T03:54:34Z")
This would be a huge improvement for many people if this new test was validated and then widely adopted. Preventive treatments for T1D would a) all of a sudden likely have many more potential volunteers for clinical tria… --- ## [If pharmas could cure T1D, would they?](https://forum.fudiabetes.org/t/if-pharmas-could-cure-t1d-would-they/3887)
**Author:** [@TiaG](https://forum.fudiabetes.org/u/TiaG)\ **Replies:** 12\ **Last updated:** [April 29, 2018, 8:08pm UTC](https://forum.fudiabetes.org/t/if-pharmas-could-cure-t1d-would-they/3887 "2018-04-29T20:08:33Z")
I thought of a post someone had on here recently where they asked whether pharmas would work on curing diseases if they could. It seems for orphan diseases, the big drug makers have decided it’s just not worth it: https… --- ## [Research: muscle mitochondria damaged even in active, healthy youngsters with T1D](https://forum.fudiabetes.org/t/research-muscle-mitochondria-damaged-even-in-active-healthy-youngsters-with-t1d/3921)
**Author:** [@TiaG](https://forum.fudiabetes.org/u/TiaG)\ **Replies:** 12\ **Last updated:** [April 24, 2018, 2:19am UTC](https://forum.fudiabetes.org/t/research-muscle-mitochondria-damaged-even-in-active-healthy-youngsters-with-t1d/3921 "2018-04-24T02:19:24Z")
Not sure how significant the effect was – but it’s disheartening that even regular physical activity doesn’t seem to mitigate this mitochondrial dysfunction. Although maybe it does and they just haven’t figured out the r… --- ## [Talk about hyperbole](https://forum.fudiabetes.org/t/talk-about-hyperbole/3934)
**Author:** [@TiaG](https://forum.fudiabetes.org/u/TiaG)\ **Replies:** 6\ **Last updated:** [April 23, 2018, 7:51pm UTC](https://forum.fudiabetes.org/t/talk-about-hyperbole/3934 "2018-04-23T19:51:22Z")
Headline: Revolutionary ‘Artificial Pancreas’ Is Proving to Be Incredible For Type 1 Diabetics Dek: Thank you, science! … the small print… “The team found that volunteers trialling this class of device spent roughly 1… --- ## [Stem Cell Educator Starts Two Phase-II Trials](https://forum.fudiabetes.org/t/stem-cell-educator-starts-two-phase-ii-trials/3898)
**Author:** [@joshualevy](https://forum.fudiabetes.org/u/joshualevy)\ **Replies:** 1\ **Last updated:** [April 15, 2018, 6:50pm UTC](https://forum.fudiabetes.org/t/stem-cell-educator-starts-two-phase-ii-trials/3898 "2018-04-15T18:50:29Z")
I just published a new blog posting: Stem Cell Educator Starts Two Phase-II Trials --- ## [The WORST news in a while](https://forum.fudiabetes.org/t/the-worst-news-in-a-while/3659)
**Author:** [@TiaG](https://forum.fudiabetes.org/u/TiaG)\ **Replies:** 31\ **Last updated:** [March 14, 2018, 8:24pm UTC](https://forum.fudiabetes.org/t/the-worst-news-in-a-while/3659 "2018-03-14T20:24:18Z")
Apparently coffee is not so great for Type 1s – there have to be some holes in this research, right??? https://www.medscape.com/viewarticle/893541 --- ## [T1D and the risk of serious infection](https://forum.fudiabetes.org/t/t1d-and-the-risk-of-serious-infection/3588)
**Author:** [@TiaG](https://forum.fudiabetes.org/u/TiaG)\ **Replies:** 53\ **Last updated:** [March 12, 2018, 10:00pm UTC](https://forum.fudiabetes.org/t/t1d-and-the-risk-of-serious-infection/3588 "2018-03-12T22:00:32Z")
Sobering results: https://www.infectiousdiseaseadvisor.com/sepsis/increased-risk-serious-infections-type-1-diabetes/article/738797/ --- ## [New with updates on Diamyd, Verapamil, and Vitamin D](https://forum.fudiabetes.org/t/new-with-updates-on-diamyd-verapamil-and-vitamin-d/3652)
**Author:** [@joshualevy](https://forum.fudiabetes.org/u/joshualevy)\ **Replies:** 2\ **Last updated:** [March 7, 2018, 5:42am UTC](https://forum.fudiabetes.org/t/new-with-updates-on-diamyd-verapamil-and-vitamin-d/3652 "2018-03-07T05:42:28Z")
Just wrote a new blog, which is a bunch of small updates on research aimed at curing type-1 diabetes. Coverage includes Diamyd, Verapamil, and Vitamin D: --- ## [Update On Two AAT Clinical Trials](https://forum.fudiabetes.org/t/update-on-two-aat-clinical-trials/3511)
**Author:** [@joshualevy](https://forum.fudiabetes.org/u/joshualevy)\ **Replies:** 4\ **Last updated:** [February 25, 2018, 11:08am UTC](https://forum.fudiabetes.org/t/update-on-two-aat-clinical-trials/3511 "2018-02-25T11:08:05Z")
This is a update on two AAT (Alpha-1 Antitrypsin) clinical trials, with a little more general summary of AAT status at the end. AAT is an anti-inflammatory/immunomodulatory drug, which the body makes naturally, and whic… --- ## [The Cellular Networking, Integration and Processing (CNIP) Project: a potential cure](https://forum.fudiabetes.org/t/the-cellular-networking-integration-and-processing-cnip-project-a-potential-cure/3276)
**Author:** [@docslotnick](https://forum.fudiabetes.org/u/docslotnick)\ **Replies:** 9\ **Last updated:** [February 8, 2018, 7:02pm UTC](https://forum.fudiabetes.org/t/the-cellular-networking-integration-and-processing-cnip-project-a-potential-cure/3276 "2018-02-08T19:02:16Z")
The cure that I’m betting on is the CNIP (Cellular Networking Integration and Processing) model in the works at Syner-III. It involves reprogramming some the patient’s non insulin secreting pancreatic cells to produce in… --- ## [University of Alberta Starts the Mozobil Phase-I Clinical Trial](https://forum.fudiabetes.org/t/university-of-alberta-starts-the-mozobil-phase-i-clinical-trial/3416)
**Author:** [@joshualevy](https://forum.fudiabetes.org/u/joshualevy)\ **Replies:** 4\ **Last updated:** [February 4, 2018, 4:04am UTC](https://forum.fudiabetes.org/t/university-of-alberta-starts-the-mozobil-phase-i-clinical-trial/3416 "2018-02-04T04:04:46Z")
Note: I’m calling this the Mozobil study, because that is the trade name of one key drug being used, and I don’t have a better name for the study. However, as described below, this study is using five different drugs. … --- ## [Viacyte heterogeneous Beta cell transplant research project](https://forum.fudiabetes.org/t/viacyte-heterogeneous-beta-cell-transplant-research-project/3267)
**Author:** [@Michel](https://forum.fudiabetes.org/u/Michel)\ **Replies:** 9\ **Last updated:** [January 18, 2018, 6:51pm UTC](https://forum.fudiabetes.org/t/viacyte-heterogeneous-beta-cell-transplant-research-project/3267 "2018-01-18T18:51:47Z")
Viacyte, a San Diego company, is pioneering a pilot project with U of Minneapolis and UBC-Vancouver, implanting heterogeneous beta cells issued from embryonic stem cells into patients’ arms: ViaCyte’s approach is … --- ## [Annexin A1 attenuates microvascular complications in type 1 diabetes](https://forum.fudiabetes.org/t/annexin-a1-attenuates-microvascular-complications-in-type-1-diabetes/3247)
**Author:** [@docslotnick](https://forum.fudiabetes.org/u/docslotnick)\ **Replies:** 6\ **Last updated:** [January 16, 2018, 4:31pm UTC](https://forum.fudiabetes.org/t/annexin-a1-attenuates-microvascular-complications-in-type-1-diabetes/3247 "2018-01-16T16:31:07Z")
Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes Just came across this article concerning the proposed use of Annexin A1, an anti inflammation … --- ## [Childhood increase of vitamin D intake linked to reduced risk of type 1 diabetes](https://forum.fudiabetes.org/t/childhood-increase-of-vitamin-d-intake-linked-to-reduced-risk-of-type-1-diabetes/3073)
**Author:** [@Katers87](https://forum.fudiabetes.org/u/Katers87)\ **Replies:** 16\ **Last updated:** [January 6, 2018, 4:55am UTC](https://forum.fudiabetes.org/t/childhood-increase-of-vitamin-d-intake-linked-to-reduced-risk-of-type-1-diabetes/3073 "2018-01-06T04:55:59Z")
--- ## [Genetic engineering a cure for T1D?](https://forum.fudiabetes.org/t/genetic-engineering-a-cure-for-t1d/3098)
**Author:** [@TiaG](https://forum.fudiabetes.org/u/TiaG)\ **Replies:** 10\ **Last updated:** [January 5, 2018, 1:42pm UTC](https://forum.fudiabetes.org/t/genetic-engineering-a-cure-for-t1d/3098 "2018-01-05T13:42:40Z")
Add it to the pile of potential treatment angles: I’d be more excited about this if it had some feasible way to reprogram the immune system. The way I see it, putting some insulin-producing cells into the pancreas is … --- ## [Study: baby formula from cow milk doesn't increase incidence of T1 diabetes](https://forum.fudiabetes.org/t/study-baby-formula-from-cow-milk-doesnt-increase-incidence-of-t1-diabetes/3057)
**Author:** [@Michel](https://forum.fudiabetes.org/u/Michel)\ **Replies:** 10\ **Last updated:** [January 3, 2018, 4:33pm UTC](https://forum.fudiabetes.org/t/study-baby-formula-from-cow-milk-doesnt-increase-incidence-of-t1-diabetes/3057 "2018-01-03T16:33:52Z")
This powerful study, from researchers with an outstanding background in this specific area, makes it appear less likely that the whole proteins in baby formula made from cow’s milk increase the risk of a later T1 diabete… --- ## [Atrial Fibrillation and T1D (and T2D), too](https://forum.fudiabetes.org/t/atrial-fibrillation-and-t1d-and-t2d-too/2995)
**Author:** [@TiaG](https://forum.fudiabetes.org/u/TiaG)\ **Replies:** 5\ **Last updated:** [December 28, 2017, 8:01pm UTC](https://forum.fudiabetes.org/t/atrial-fibrillation-and-t1d-and-t2d-too/2995 "2017-12-28T20:01:29Z")
Interesting study. Seems that atrial fibrillation is associated with Type 1 Diabetes, and indirectly linked with A1C but only if people sustained end organ damage --- ## [Coronary Artery Calcium Scores](https://forum.fudiabetes.org/t/coronary-artery-calcium-scores/2529)
**Author:** [@lh378](https://forum.fudiabetes.org/u/lh378)\ **Replies:** 29\ **Last updated:** [December 14, 2017, 3:26am UTC](https://forum.fudiabetes.org/t/coronary-artery-calcium-scores/2529 "2017-12-14T03:26:05Z")
At my recent endo visit, it was brought up that I may benefit from cardiac calcium scoring. My risk factors are LDL cholesterol (135) outside of normal limits and total cholesterol (263) outside of normal limits, and o… --- ## [IMCY-0098 Starts a Phase-I Clinical Trial](https://forum.fudiabetes.org/t/imcy-0098-starts-a-phase-i-clinical-trial/2760)
**Author:** [@joshualevy](https://forum.fudiabetes.org/u/joshualevy)\ **Replies:** 0\ **Last updated:** [December 2, 2017, 5:47pm UTC](https://forum.fudiabetes.org/t/imcy-0098-starts-a-phase-i-clinical-trial/2760 "2017-12-02T17:47:44Z")
I wrote a blog on IMCY-0098 a drug being tested by Imcyse to try to cure type-1 diabetes. You can read it here: http://cureresearch4type1diabetes.blogspot.com/2017/11/imcy-0098-starts-phase-i-clinical-trial.html --- ## [If you could "select" children to avoid the risk of diabetes](https://forum.fudiabetes.org/t/if-you-could-select-children-to-avoid-the-risk-of-diabetes/2546)
**Author:** [@TiaG](https://forum.fudiabetes.org/u/TiaG)\ **Replies:** 29\ **Last updated:** [November 28, 2017, 4:29pm UTC](https://forum.fudiabetes.org/t/if-you-could-select-children-to-avoid-the-risk-of-diabetes/2546 "2017-11-28T16:29:15Z")
would you? This article seems to suggest that such a future may not be so far away… [Previous page](https://forum.fudiabetes.org/c/diabetes-type-1-lada/t1-research/62.md?page=2) [Next page](https://forum.fudiabetes.org/c/diabetes-type-1-lada/t1-research/62.md?page=4)